Research strategy and progression of microarray analysis in transcriptology of cutaneous squamous cell carcinoma / 解放军医学杂志

Cutaneous squamous cell carcinoma (cSCC) is one of the malignant tumors originated from keratinocytes. In recent years, bioinformatics has been widely used in the research of cSCC, including genomics, transcriptionomics and proteomics. Transcriptionomics is to study the function and structure of genes at the overall level, and reveal the molecular mechanism of specific biological processes. At present, microarray (gene chip) analysis method has been studied deeply. The selection and processing of gene chip expression database, online analysis platform and related software, as well as the latest research progress of gene expression chip in cSCC have herewith been reviewed in present paper.